Latest paper from group: Investigating the In Vivo Antimicrobial Activity of a Self-Assembling Peptide Hydrogel Using a Galleria mellonella Infection Model
Our latest research paper is now freely available via the journal ACS Omega, whereby we use an innovative waxworm (Galleria mellonella) model as an alternative to mammalian/vertebrate testing. The following assay can be very simply performed without any specific ethical approval or animal licenses. We successfully employed the methods outlined to study the antimicrobial efficacy and toxicity of our (naphthalene-2-ly)-acetyl-diphenylalanine-dilysine-OH (NapFFKK-OH) peptide hydrogel.
Always of major interest in our conference presentations, we hope we now are able to provide a validated method to study new Active Pharmaceutical Ingredients.
We’d like to thank all those who contributed!!
Our peptide hydrogel research wins Controlled Release Society’s 2020 People’s Choice Award
We are excited to hear our research on the use of peptide hydrogels for HIV/AIDs drug delivery won the overall CRS People’s Choice Award at the recent CRS virtual meeting. The presentation, as well as our other work, is available to conference participants by clicking the relevant title below. Poster: Poster number 63. Peptide-like […]
Latest hydrogel work published in Chemical Communications
Our latest collaborative work on entitled “Tuning the antimicrobial activity of low molecular weight hydrogels using dopamine autoxidation,” has been accepted within Chemical Communications. This work was led by Emily Cross and represents a collaboration with Prof Dave Adams’ Group at the School of Chemistry University of Glasgow and is freely available here. Thanks again […]
Latest publication: Pharmaceutical formulation and characterization of dipeptide nanotubes for drug delivery applications
Our latest paper has been published in the journal Macromolecular Bioscience focusing on formulating peptide nanotubes using mild techniques to improve potential for pharmaceutical upscale. Paper can be accessed here: https://doi.org/10.1002/mabi.202000115 Abstract Peptide nanotubes are promising materials for a variety of biomedical applications with ultrashort (≤7 amino acids) forms providing particular promise for clinical translation. […]
Group receive major funding from EPSRC to develop peptide-like hydrogels for combined HIV-contraceptive therapy
We are excited to announce support from the Engineering and Physical Sciences Research Council (EPSRC) to develop of peptide-like hydrogels for use as a long-acting injectable delivery platform for combined HIV-contraceptive drug delivery. Total support (£766,542) will allow further development of our peptide-mimetic platforms in a key healthcare area in collaboration with our co-investigators at […]
Our book, Hydrogels: Design, synthesis & application in drug delivery & regenerative medicine, available now!
If you are interested in knowing more about the potential applications of our hydrogels, remember to check out our recent book “Hydrogels: Design, synthesis & application in drug delivery & regenerative medicine,” co-edited alongside Dr Raj Thakur and Prof Ryan Donnelly. Thanks to all those who contributed.
Exciting new lab facilities
We are currently moving into our new lab facilities in the School of Pharmacy’s McClay Research Centre, including a new synthesis and microbiology lab.
Funding for Medical Research Council: Confidence in Concept Project
We are happy to announce our group has received funding as part of the MRC CiC programme (£67,867) to study the use of antiretroviral drugs in HIV/AIDs prevention alongside our industry partners. Funding will enable a Research Fellow to work within our group on this project for one year. We should hopefully be in a […]