Available Research Fellow Position
Research Fellow positions
We are looking for a Research Fellow to support the development of an enzyme-responsive peptide-mimetic hydrogel for the sustained parenteral delivery of antiretroviral drugs for HIV/AIDs. This is an MRC funded project with support available for a one year post (until 30 June 2021).
Deadline: Monday 15th June 2020
Salary: £33,797 – £36,914 per annum
We cannot accept applications directly via email, they must go through the University’s HR system. Please apply using link below.
The successful candidate will design, synthesise and characterise peptide-mimetic hydrogelator platforms suitable for the sustained parenteral delivery of antiretroviral drugs. Such techniques will include solid/liquid phase peptoid synthesis and purification, formulation, microscopy (TEM, SEM), spectroscopy (FTIR, CD, UV/Vis, NMR, Mass spectroscopy), oscillatory rheology, cell culture and drug release (HPLC).
The successful Research Fellow must have:
- Or be about to obtain a PhD in Chemistry, Biochemistry, Chemical Engineering, Pharmaceutical Chemistry, Pharmaceutical Sciences or closely related area.
- At least 3 years recent relevant practical research experience of peptoid and peptide-mimetic synthesis, advanced methods of drug conjugation, purification and identification.
- Experience in formulating peptide-mimetic hydrogel systems.
- Experience in drug purification, release experiments and quantification by HPLC.
Latest hydrogel work published in Chemical Communications
Our latest collaborative work on entitled “Tuning the antimicrobial activity of low molecular weight hydrogels using dopamine autoxidation,” has been accepted within Chemical Communications. This work was led by Emily Cross and represents a collaboration with Prof Dave Adams’ Group at the School of Chemistry University of Glasgow and is freely available here. Thanks again […]
Our peptide hydrogel research wins Controlled Release Society’s 2020 People’s Choice Award
We are excited to hear our research on the use of peptide hydrogels for HIV/AIDs drug delivery won the overall CRS People’s Choice Award at the recent CRS virtual meeting. The presentation, as well as our other work, is available to conference participants by clicking the relevant title below. Poster: Poster number 63. Peptide-like […]
Latest publication: Pharmaceutical formulation and characterization of dipeptide nanotubes for drug delivery applications
Our latest paper has been published in the journal Macromolecular Bioscience focusing on formulating peptide nanotubes using mild techniques to improve potential for pharmaceutical upscale. Paper can be accessed here: https://doi.org/10.1002/mabi.202000115 Abstract Peptide nanotubes are promising materials for a variety of biomedical applications with ultrashort (≤7 amino acids) forms providing particular promise for clinical translation. […]
Group receive major funding from EPSRC to develop peptide-like hydrogels for combined HIV-contraceptive therapy
We are excited to announce support from the Engineering and Physical Sciences Research Council (EPSRC) to develop of peptide-like hydrogels for use as a long-acting injectable delivery platform for combined HIV-contraceptive drug delivery. Total support (£766,542) will allow further development of our peptide-mimetic platforms in a key healthcare area in collaboration with our co-investigators at […]
Our book, Hydrogels: Design, synthesis & application in drug delivery & regenerative medicine, available now!
If you are interested in knowing more about the potential applications of our hydrogels, remember to check out our recent book “Hydrogels: Design, synthesis & application in drug delivery & regenerative medicine,” co-edited alongside Dr Raj Thakur and Prof Ryan Donnelly. Thanks to all those who contributed.
Our EPSRC research selected as case study
Our research into long-acting peptide hydrogel drug delivery implants has been selected as a case study by the EPSRC for their Developing New Therapies Grand Challenge. Thanks to all of those involved in this multidisciplinary project and it’s great to see our work moving forward towards future use in patients. Please find a link to the […]
We will be presenting at the Controlled Release Society 2020 Virtual Meeting!
Whilst we were looking forward to the opportunity to attend CRS 2020 in Las Vegas, the ongoing pandemic has meant that we have had to cancel our travel plans. However, we are excited to support the Controlled Release Society take part in this innovative virtual CRS initiative. We will be presenting the following […]