About Our Work

Our research focuses on the the design and development of self-assembling nanostructures/platforms for biomedical applications based on the building blocks of life, primarily peptides and peptide-like molecules. These structures have the ability to form nanofibrous hydrogels or nanotubular structures with high surface to volume ratios in the presence of specific physiological stimuli (e.g. pH, temperature, enzymes). They have huge potential within the fields of drug delivery and biomaterials with the group’s focus primarily on the development of antimicrobial/anticancer technologies, sustained release drug delivery systems and molecules with the ability to transverse the biological barriers (e.g. blood-brain barrier, outer membrane of Gram-negative bacteria). Our work is funded by a variety of sources including the Wellcome Trust, the Royal Society, the Society for Applied Microbiology, the Biochemical Society and Intertrade Ireland.