Latest hydrogel work published in Chemical Communications
Our latest collaborative work on entitled “Tuning the antimicrobial activity of low molecular weight hydrogels using dopamine autoxidation,” has been accepted within Chemical Communications.
Thanks again to all those involved!
Abstract: We present a method to trigger the formation of dipeptide-based hydrogels by the simple addition of dopamine. Dopamine undergoes oxidation in air, reducing the pH to induce gelation. The production of polydopamine and release of reactive oxygen species such as hydrogen peroxide confers antimicrobial activity. Gel stiffness can be controlled by modulating the initial starting pH of the gelator solution. We can use this method to tune the antimicrobial activity of the gels, with gels that are less stiff demonstrating increased bactericidal efficacy against Gram-positive bacteria.
Advanced Science News Coverage and Advanced Healthcare Materials paper
Our recent research into using peptide hydrogels as long-acting injectable implants for HIV/AIDS drug delivery has be covered by Advanced Science News. This provides an oversight of our most recent publication within Advanced Healthcare Materials. A link to both can be found below: Advanced Science News Advanced Healthcare Materials
Our EPSRC research selected as case study
Our research into long-acting peptide hydrogel drug delivery implants has been selected as a case study by the EPSRC for their Developing New Therapies Grand Challenge. Thanks to all of those involved in this multidisciplinary project and it’s great to see our work moving forward towards future use in patients. Please find a link to the […]
Publication of group’s educational paper on industrial pharmaceutical formulation
Our group’s educational paper “Development of a teaching model to advance skills in industrial pharmaceutical formulation and regulatory aspects,” has now been published in Currents in Pharmacy Teaching and Learning. A free link to the article is provided below, valid before January 26th 2019. Thanks to all those who contributed to the article, especially the BSc […]
New website launch!!
Welcome to our new and improved website! We hope this provides an accessible means to which we can communicate our research to a wider audience. Please check back regularly for important updates from our group. We’d like to thank Artisan Web Design Belfast for their help in constructing the site and the Royal Society for providing […]